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NOTICIAS CIENCIAS FISIOLÓGICAS
American Journal Of Physiology
- HIF2α: the interface between oxygen-sensing systems in physiology and pathology 13/02/2025Physiology, Ahead of Print.Tammie Bishop
- Synthetic forms most beautiful: engineering insights into self-organization. 12/02/2025Physiology, Ahead of Print.Zhejing Xu
- Utilizing Omic Data to Understand Integrative Physiology 12/02/2025Physiology, Ahead of Print.Mark A Knepper
- SCRaMbLE: a versatile tool for genome manipulation 12/02/2025Physiology, Ahead of Print.Li Cheng
- Regulation of stem cell function by NAD+ 05/02/2025Physiology, Ahead of Print.Yufan Feng
- DNA Methylation in Long-term Memory 05/02/2025Physiology, Ahead of Print.Xinyue Chen
- Immune Aging and Its Implication for Age-Related Disease Progression 31/01/2025Physiology, Ahead of Print.Yuki Sato
- The Integrative Physiology of Hormone Signaling: Insights from Insect models 31/01/2025Physiology, Ahead of Print.Takashi Koyama
- APS Initiatives and Milestones: a Year in Review and a Look Ahead 29/01/2025Physiology, Volume 40, Issue 2, Page 000-000, March 2025.Timothy Musch
- Piezo1: the Force Awakens—How Red Blood Cells Sense and Respond to Mechanical Stress 21/01/2025Physiology, Volume 40, Issue 2, Page 000-000, March 2025.Lennart Kuck
Journal of Physiology
- The visual representation of 3D orientation in macaque areas STPp and VPS 14/02/2025The Journal of Physiology, EarlyView.Rong Wang, Bin Zhao, Aihua Chen
- In vivo calcium imaging reveals directional sensitivity of C‐low threshold mechanoreceptors 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 895-908, 15 February 2025.Evangelia Semizoglou, Laure Lo Re, Steven J. Middleton, Jimena Perez‐Sanchez, Tommaso Tufarelli, David L. Bennett, Kim I. Chisholm
- Critical closing pressure and resistance‐area product as markers of cerebral autoregulation dynamics (S.J. Payne) 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 1009-1010, 15 February 2025.Ronney B. Panerai, Jatinder S. Minhas, Osian Llwyd, Angela S.M. Salinet, Thompson G. Robinson
- From human to superhuman: the impact of the microbiome on physiology 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 797-807, 15 February 2025.Stephen J. Keely, Paul D. Cotter, Annika Wahlstrom, Harriët Schellekens, David Weinkove, Kim E. Barrett
- Decoding platelet loss in the hypoxic brain: What could go wrong? 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 781-783, 15 February 2025.Spencer G. Farstad, Spencer J. Skaper
- Corticolimbic structures activation during preparation and execution of respiratory manoeuvres in voluntary olfactory sampling: An intracranial EEG study 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 989-1006, 15 February 2025.Jules Granget, Marie Cécile Niérat, Katia Lehongre, Virginie Lambrecq, Valerio Frazzini, Vincent Navarro, Nathalie Buonviso, Thomas Similowski
- Cortical coding of gustatory and thermal signals in active licking mice 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 909-928, 15 February 2025.Audrey N. Nash, Morgan Shakeshaft, Cecilia G. Bouaichi, Katherine E. Odegaard, Tom Needham, Martin Bauer, Richard Bertram, Roberto Vincis
- Human cortical high‐gamma power scales with movement rate in healthy participants and stroke survivors 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 873-893, 15 February 2025.Benjamin Haverland, Lena S. Timmsen, Silke Wolf, Charlotte J. Stagg, Lukas Frontzkowski, Robert Oostenveld, Gerhard Schön, Jan Feldheim, Focko L. Higgen, Christian Gerloff, Robert Schulz, Till R. Schneider, Bettina C. Schwab, Fanny Quandt
- Heat boost: therapeutic approach for skeletal muscle health and postprandial mechanisms in older adults 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 789-791, 15 February 2025.Marcos S. Keefe, Mario I. Hernandez, Alexandra P. Brojanac, Kelly B. Elliott, Ruben E. Moya, Ryan A. Dunn
- The place around me is (not) understood: Musings of an active single neurone 14/02/2025The Journal of Physiology, Volume 603, Issue 4, Page 775-777, 15 February 2025.Oscar Sacchi
Frontiers in Physiology
- The effect of transcranial pulse current stimulation on the accumulation of exercise-induced fatigue in college students after moderate intensity exercise evidence from central and peripheral sourcesObjectiveTo investigate the intervention effect of cranial pulse current stimulator (tPCS) on fatigue accumulation after moderate-intensity exercise by using blood analysis and functional near-infrared spectroscopy, and to analyze the type and magnitude of the fatigue effect of tPCS on fatigue in combination with behavioral performance.MethodsNinety healthy college students were randomly and equally divided into an […]
- On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronautsHuman spaceflight subjects the body to numerous and unique challenges. Astronauts frequently report a sense of sinonasal congestion upon entering microgravity for which the exact pathomechanisms are unknown. However, cephalad fluid shift seems to be its primary cause, with CO2 levels and environmental irritants playing ancillary roles. Current management focuses on pharmacotherapy comprising oral and […]
- Laboratory comparison of consumer-grade and research-established wearables for monitoring heart rate, body temperature, and physical acitivity in sub-Saharan AfricaBackgroundConsumer-grade wearables are becoming increasingly popular in research and in clinical contexts. These technologies hold significant promise for advancing digital medicine, particularly in remote and rural areas in low-income settings like sub-Saharan Africa, where climate change is exacerbating health risks. This study evaluates the data agreement between consumer-grade and research-established devices under standardized conditions.MethodsTwenty-two participants […]
- Trimethylamine N-oxide (TMAO) acutely alters ionic currents but does not increase cardiac cell deathBackgroundTrimethylamine N-oxide (TMAO) is a product of the action of gut microbiota on choline and other choline-containing compounds ingested in the diet. The presence of TMAO at high concentrations has been reported in the blood of patients with cardiovascular disease, suggesting the role for TMAO as either a marker or causative agent of the disease. […]
- Mechanisms of blood flow restriction training for knee pain: a mini reviewKnee pain, affecting an estimated 654 million people worldwide, so blood flow restriction training (BFRT) is catching the spotlight as an effective intervention. Evidence continues to demonstrate the effectiveness of BFRT in managing knee pain. However, the mechanism by which BFRT alleviates knee pain remains unclear, thereby limiting its application in clinical pain management. This […]
- Alteration of mitochondrial function in arthropods during arboviruses infection: a review of the literatureArthropods serve as vectors for numerous arboviruses responsible for diseases worldwide. Despite their medical, veterinary, and economic significance, the interaction between arboviruses and arthropods remains poorly understood. Mitochondria in arthropods play a crucial role by supplying energy for cell survival and viral replication. Some arboviruses can replicate within arthropod vectors without harming the host. Successful […]
- A four-compartment controller model of muscle fatigue for static and dynamic tasksIntroductionCompartment based models of muscle fatigue have been particularly successful in accurately modeling isometric (static) tasks or actions. However, dynamic actions, which make up most everyday movements, are governed by different central and peripheral processes, and must therefore be modeled in a manner accounting for the differences in the responsible mechanisms. In the literature, a […]
- The role of starting knee angle in squat jump force-velocity profiles: interactions with subjects’ strength levels and imputed push-off distanceIntroductionThis study investigated whether differences in the force-velocity (F-v) profile obtained using Samozino’s method during squat jumps (SJ) performed at varying knee angles are influenced by subjects’ strength levels and the push-off distance (HpO) used in the analysis.MethodsTwenty-one resistance-trained men were classified as stronger (n = 10) or weaker (n = 11) based on the […]
- Within- and between-day test–retest reliability of responses to rapid bilateral anterolateral magnetic phrenic nerve stimulation in healthy humans (ReStim)BackgroundMechanical ventilation can lead to lung injury and diaphragmatic dysfunction. Rapid bilateral anterolateral magnetic phrenic nerve stimulation (rBAMPS) may attenuate both of the aforementioned issues by inducing diaphragm activation. However, in order for rBAMPS to become part of standard of care, the reliability of inspiratory responses to rBAMPS needs to be established.MethodsEighteen healthy participants (9F) […]
- An overview of hereditary spherocytosis and the curative effects of splenectomyHereditary spherocytosis is a common hemolytic anemia with different severity. The causes of hereditary spherocytosis are mutations in genes that encode red blood cell (RBC) membrane and cytoskeletal proteins, including ankyrin-1, Band 3 (or AE1), α spectrin, β spectrin, and protein 4.2. Molecular defects in these proteins decrease membrane integrity, leading to vesiculation, decreased membrane […]
FISIOLOGÍA MÉDICA
- <em>fmo-4</em> promotes longevity and stress resistance via ER to mitochondria calcium regulation in <em>C. elegans</em> 14/02/2025Flavin-containing monooxygenases (FMOs) are a conserved family of xenobiotic enzymes upregulated in multiple longevity interventions, including nematode and mouse models. Previous work supports that C. elegans fmo-2 promotes longevity, stress resistance, and healthspan by rewiring endogenous metabolism. However, there are five C. elegans FMOs and five mammalian FMOs, and it is not known whether promoting […]Angela M Tuckowski
- The behavioural, physiological and biochemical responses of Lumbriculus variegatus exposed to cannabidiol (CBD) and its metabolites 14/02/2025Cannabidiol (CBD) is a major non-psychoactive cannabinoid that has been detected in environmental samples, but the ecotoxicological effects remain unknown. In this study, Lumbriculus variegatus are exposed to CBD, and its metabolites 7-hydroxy-cannabidiol (7-OH-CBD) and 7-carboxy-cannabidiol (7-COOH-CBD). In this study, toxicity, tactile stimulation to elicit stereotypical behaviours and locomotor activity are measured after 24-hour exposure […]Benjamin S Williams
- Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice 14/02/2025CONCLUSIONS: This study reveals that long-term hydrogen-rich water (HRW) consumption provides significant hepatoprotection in mice under chronic stress. HRW normalizes liver enzyme levels, enhances antioxidant capacity, and reduces lipid peroxidation and ferroptosis. It improves mitochondrial biogenesis, function, and ATP production, and attenuates apoptosis by modulating related proteins. Behavioral tests show HRW alleviates stress-induced anxiety and […]Qi He
- Hormonal Birth Control Is Associated with Altered Gut Microbiota Beta-Diversity in Physically Active Females Across the Menstrual Cycle: A Pilot Trial 14/02/2025Understanding changes to gut microbiota composition in response to hormonal birth control (HBC) may provide insight into the microbial mechanisms underlying the metabolic effects of HBC, for example, altered short-chain fatty acid (SCFA) production. Athletes' unique physiological demands may interact with these microbial mechanisms in distinct ways; however, there is limited research on HBC and […]Julian Brito
- Inhibition of the Integrated stress response by Epstein-Barr virus oncoprotein LMP1 attenuates epithelial cell differentiation and lytic viral reactivation 14/02/2025EBV infects normal oral keratinocytes (NOKs) and plays an essential role in undifferentiated nasopharyngeal carcinoma (NPC). We previously showed that the EBV oncogene, LMP1, promotes proliferation and inhibits spontaneous differentiation in telomerase-immortalized NOKs grown in growth factor-restricted conditions. Here we have further examined the phenotypes of NOKs infected with wild-type EBV (WT EBV) versus an […]Deo R Singh
- Acute fatigue in indoor court-based team sports: A systematic review 14/02/2025Fatigue in team sports has been widely researched, with a number of systematic reviews summarising the acute (i.e., within 48-hours) response in outdoor sports. However, the fatigue response to indoor court-based sports is likely to differ to outdoor sports due to smaller playing fields, harder surfaces, and greater match frequencies, thus should be considered separately […]Anthony Clark
- Maternity care providers' experiences of work-related serious events (MATES): An International survey 14/02/2025Internationally, many women experience physiological childbirth with positive experiences and good health outcomes for them and their baby. For some, due to health complications and context of childbirth they may experience or be perceived as having had a traumatic birth. Ultimately, whether an individual experiences an event as traumatic or not, is a personal experience. […]Maria Healy
- miR-455-3p has superior diagnostic potential to PSA in peripheral blood for prostate cancer 14/02/2025CONCLUSION: Our study identifies miR-455-3p as a promising diagnostic marker for PCa, outperforming PSA in terms of specificity and sensitivity. The robustness of miR-455-3p, coupled with its potential downstream targets and associated pathways, highlights its clinical significance for improved PCa diagnosis and management.Yi Cen
- Glucose-Dependent Insulinotropic Polypeptide in Incretin Physiology: Role in Health and Disease 14/02/2025Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid hormone that is synthesized and released from upper intestinal enteroendocrine K-cells in response to the ingestion of glucose or fat. The structure of GIP places it in the secretin/vasoactive intestinal polypeptide family of gastrointestinal regulatory peptides. Although originally named "gastric inhibitory polypeptide" on the basis of its […]M Michael Wolfe
- A Scenario-Adaptive Microfluidic Chip for Constructing In Vitro Models of Biological Barriers 14/02/2025Microfluidic-based in vitro physiological barrier models are capable of simulating crucial environmental factors during barrier formation, including fluid shear and geometric-level cellular cocultures, thus offering enhanced physiological fidelity relative to conventional platforms. However, the sealed structure of microfluidic barrier chips faces challenges in characterizing and monitoring the barrier performance, especially in measuring transendothelial/epithelial electrical resistance […]Yaran Chang