NOTICIAS CIENCIAS FISIOLÓGICAS

Frontiers in Physiology

• Immune niches for hair follicle development and homeostasis
  The hair follicle is a dynamic mini-organ that has specialized cycles and architectures with diverse cell types to form hairs. Previous studies for several decades have investigated morphogenesis and signaling pathways during embryonic development and adult hair cycles in both mouse and human skin. In particular, hair follicle stem cells and mesenchymal niches received major […]
• Acute physiological and psychological responses during an incremental treadmill test wearing a new upper-body sports garment with elastomeric technology
  Background: The use of elastomeric technology in sports garments is increasing in popularity; however, its specific impact on physiological and psychological variables is not fully understood. Thus, we aimed to analyze the physiological (muscle activation of the pectoralis major, triceps brachii, anterior deltoid, and rectus abdominis, capillary blood lactate, systolic and diastolic blood pressure, and […]
• Proof-of-concept model for instantaneous heart rate-drift correction during low and high exercise exertion
  Introduction: This study aimed to model below and above anaerobic threshold exercise-induced heart rate (HR) drift, so that the corrected HR could better represent V̇O2 kinetics during and after the exercise itself.Methods: Fifteen healthy subjects (age: 28 ± 5 years; V̇O2Max: 50 ± 8 mL/kg/min; 5 females) underwent a maximal and a 30-min submaximal (80% […]
• Sex-dependent regulation of mucin gene transcription and airway secretion and mechanics following intra-airway IL-13 in mice with conditional loss of club cell Creb1
  Introduction: Interleukin 13 (IL-13) is an important effector molecule in allergic asthma. IL-13-mediated mucin hypersecretion requires conversion of secretoglobin-positive club cells into goblet cells through suppression of forkhead box A2 (FOXA2) and induction of SAM pointed domain containing ETS transcription factor (SPDEF). IL-13-mediated mucin hypersecretion may also include modulation of purinergic and muscarinic receptors that […]
• Mechanism of hypoxia-induced damage to the mechanical property in human erythrocytes—band 3 phosphorylation and sulfhydryl oxidation of membrane proteins
  Introduction: The integrity of the erythrocyte membrane cytoskeletal network controls the morphology, specific surface area, material exchange, and state of erythrocytes in the blood circulation. The antioxidant properties of resveratrol have been reported, but studies on the effect of resveratrol on the hypoxia-induced mechanical properties of erythrocytes are rare.Methods: In this study, the effects of […]
• Resveratrol facilitates bone formation in high-glucose conditions
  Periodontitis is known to be affected by high-glucose conditions, which poses a challenge to periodontal tissue regeneration, particularly in bone formation. In this study, the potential effects of resveratrol (3,5,4′-trihydroxystilbene, RSV) in facilitating bone formation under high-glucose conditions after periodontitis has been investigated. We focused on the analysis of osteoblasts and periodontal ligament cells, which […]
• A porcine large animal model of radiofrequency ablation-induced left bundle branch block
  BackgroundElectrocardiographic (ECG) features of left bundle branch (LBB) block (LBBB) can be observed in up to 20%–30% of patients suffering from heart failure with reduced ejection fraction. However, predicting which LBBB patients will benefit from cardiac resynchronization therapy (CRT) or conduction system pacing remains challenging. This study aimed to establish a translational model of LBBB […]
• Correlation between epicardial adipose tissue and myocardial injury in patients with COVID-19
  Background: Many people infected with COVID-19 develop myocardial injury. Epicardial adipose tissue (EAT) is among the various risk factors contributing to coronary artery disease. However, its correlation with myocardial injury in patients diagnosed with COVID-19 remains uncertain.Methods: We examined myocardial biomarkers in population affected by COVID-19 during the period from December 2022 to January 2023. […]
• Short-term cutaneous vasodilatory and thermosensory effects of topical methyl salicylate
  Introduction:Methyl salicylate, the main compound of wintergreen oil, is widely used in topical applications. However, its vascular and thermosensory effects are not fully understood. The primary aim was to investigate the effects of topical methyl salicylate on skin temperature (Tskin), skin microcirculation (MCskin) and muscle oxygen saturation (SmO2) compared to a placebo gel. The secondary […]
• Editorial: Advances in research on aging in female infertility and pathologic pregnancy