NOTICIAS CIENCIAS FISIOLÓGICAS

Frontiers in Physiology

• NH3/NH4+ allosterically activates SLC4A11 by causing an acidic shift in the intracellular pK that governs H+(OH−) conductance
  SLC4A11 is the most abundant membrane transport protein in corneal endothelial cells. Its functional presence is necessary to support the endothelial fluid pump that draws fluid from the corneal stroma, preventing corneal edema. Several molecular actions have been proposed for SLC4A11 including H2O transport and cell adhesion. One of the most reproduced actions that SLC4A11 […]
• Lithium-induced apoptotic cell death is not accompanied by a noticeable inflammatory response in the kidney
  Lithium (Li+) therapy is a valuable tool in psychiatric practice that remains underutilized due to safety concerns. Excessive plasma Li+ levels are nephrotoxic and can trigger a local immune response. Our understanding of the immunomodulatory effects of Li+ in the kidney is fragmentary. Here, we studied how immune mechanisms contribute to the development of Li+-induced […]
• Post-activation performance enhancement (PAPE) protocols do not further increase jumping performance beyond warm-up effects: findings from three acute randomized crossover trials
  Introduction: Post-activation performance enhancement (PAPE) cannot be clearly distinguished from and may be explained in large by warm-up effects. To disentangle PAPE from a systemic warm-up effect, we conducted three randomized crossover trials (RCT).Methods: Each RCT consisted of a familiarization/one-repetition-maximum (1RM) assessment session followed by two interventional sessions (random order). In Study I, 18 participants […]
• Muscle reoxygenation is slower after higher cycling intensity, and is faster and more reliable in locomotor than in accessory muscle sites
  IntroductionWearable near-infrared spectroscopy (NIRS) can be used during dynamic exercise to reflect the balance of muscle oxygen delivery and uptake. This study describes the behaviour and reliability of postexercise reoxygenation with NIRS as a function of exercise intensity at four muscle sites during an incremental cycling test. We discuss physiological components of faster and slower […]
• Effects of transcranial direct current stimulation combined with Bosu ball training on the injury potential during drop landing in people with chronic ankle instability
  PurposeTo investigate the effects of transcranial direct current stimulation (tDCS) combined with Bosu ball training on the injury potential during drop landing in people with chronic ankle instability (CAI).MethodsA total of 40 participants with CAI were recruited and randomly divided into the tDCS + Bosu and Bosu groups. The people in the tDCS + Bosu […]
• The arrhythmic substrate of hypertrophic cardiomyopathy using ECG imaging
  Introduction: Patients with hypertrophic cardiomyopathy (HCM) are at risk for lethal ventricular arrhythmia, but the electrophysiological substrate behind this is not well-understood. We used non-invasive electrocardiographic imaging to characterize patients with HCM, including cardiac arrest survivors.Methods: HCM patients surviving ventricular fibrillation or hemodynamically unstable ventricular tachycardia (n = 17) were compared to HCM patients without […]
• Fundamental equations and hypotheses governing glomerular hemodynamics
  The glomerular filtration rate (GFR) is the outcome of glomerular hemodynamics, influenced by a series of parameters: renal plasma flow, resistances of afferent arterioles and efferent arterioles (EAs), hydrostatic pressures in the glomerular capillary and Bowman’s capsule, and plasma colloid osmotic pressure in the glomerular capillary. Although mathematical models have been proposed to predict the […]
• Fibroadipogenic progenitors: a potential target for preventing breast muscle myopathies in broilers
  Genetic selection for high growth rate, breast muscle yield, and feed efficiency in modern broilers has been a double-edged sword. While it has resulted in marked benefits in production, it has also introduced widespread incidence of breast muscle myopathies. Broiler myopathies are phenotypically characterized by myodegeneration and fibrofatty infiltration, which compromise meat quality. These lesions […]
• Evidence of spontaneous cardiac-locomotor coupling during daily activities in healthy adults
  IntroductionOne way to improve exercise performance and protect heart health is the extended synchronization of the stepping with the diastolic phase of the cardiac cycle. Cardiac-locomotor coupling (CLC) happens when the step rate (SR) equals the heart rate (HR). The extent of CLC in daily life is unknown. This study aims to analyze spontaneous occurrences […]
• Event-related pupillary response-based authentication system using eye-tracker add-on augmented reality glasses for individual identification
  This study aimed at developing a noncontact authentication system using event-related pupillary response (ErPR) epochs in an augmented reality (AR) environment. Thirty participants were shown in a rapid serial visual presentation consisting of familiar and unknown human photographs. ErPR was compared with event-related potential (ERP). ERP and ErPR amplitudes for familiar faces were significantly larger […]